Well, for a while now we've noticed how difficult it can be to keep with five updates a week. So you have to make a decision that suits best with reality.
How frequently can you consistently update? How much will your income suffer from the reduction of updates? How much will the enjoyment of your own personal life will be affected?
As I see it, I imagine that the third question is extremely important to you, which is why you can't always manage the five updates a week you desired. Just do what you think will work best for you in the long run. As long as you don't skip updates, your fans will most likely be okay with whatever resolution you pick.
Also, there's also the choice of updating four times a week. Perhaps you can just gradually scale back and see what works best for you
If your switching to a tri weekly update on Roomie are you going to be working on your KIGO comic more then? I love both comics and your art style. Mainly I just want to see more of it. Yeah I know I'm a greedy little Irish man, but hey good story and art are hard to find. SO when I find both, at the same time, I hold on to it for all I'm worth. But it all comes down to what you are most comfortable with, and what ever you decide I will be happy that you still share your creativity with us internet people.